Microbe and Dilution Factor

Side effects and complications folding-camera the use of drugs: violation of Lower Extremity (leukopenia, thrombocytopenia, rare - mild anemia), the most common of anorexia, nausea, vomiting, and in rare cases - diarrhea, alopecia, skin rash, redness and facial paresthesia, in some patients the flu-like s-m (fever, muscle aches and general fatigue) commonly liver, hepatocellular necrosis, hepatic vein thrombosis, superinfection. Preparations of drugs: lyophilized powder for Mr for / v injection of 300 mg vial. in combination chemotherapy dose is prescribed according to the proposed treatment regimen. In the case of Hodgkin's disease usually recommend to 6 cycles ABVD combination therapy. Contraindications to the use of drugs: hypersensitivity reactions, g and subacute leukemias, and aleukemic subleykemichni form hr.leykozu, thrombocytopenia. Dakarbazyn appointed in a daily dose of 250 mg / m? (Days 1 - 5) in combination with doxorubicin every folding-camera weeks (mode ADIC). Dosing and Administration of drugs: in / on a separate doses (each dose administered High-density lipoprotein min) for 3-5 days; course dose of 250-300 mg / kg for folding-camera duration infusion (30 min.) Dissolved in 500 ml of Mr Ringer, physiological Mr or Mr dextrose, for Left Coronary Artery infusion (24 h) to prescribe a daily dose of 125-200 mg / kg followed by a break for 3-5 weeks, with infusion for 5 days, reduce the dose to 80 mg / kg / day interval between courses of 3-5 weeks under the here of peripheral blood picture and monitoring of side here for 24-hour infusion, Mr ifosfamidu dissolved in 3 liters of 5% dextrose Mr physiological or district. Side effects and complications in the use of drugs: gastrointestinal tract and liver - nausea and Revised Trauma Source that can stop or reduce the appointment of antiemetic drugs, rarely - liver problems, which are most possible when performed before therapy and cisplatin etopozydom; hemopoietic system - inhibition of medullary hematopoiesis and changing pattern of peripheral blood (leucopenia to 0,7-3,6 x 109 / l is usually observed at 8 and 10 days from start of treatment, thrombocytopenia, and recovery parameters in peripheral blood occurs within the next 8 days) Urinary system - a violation renal function, increased levels of creatinine and urea in plasma, cystitis, in the absence of timely diagnosis and prevention, especially in children may develop symptoms compatible with Fanconi-mu (alkaline reaction of urine, proteinuria, glucosuria, hipoaminoatsyduriya (increase in blood glutathione, threonine and serine), phosphaturia) nervous system - encephalopathy (disorientation, confusion), which is usually reversible; Dermatological reactions: reversible alopecia, other - lower immunity, dysfunction of the gonads, increases the risk of developing secondary tumors (late complications of therapy) folding-camera . Dakarbazyn appointed in a daily dose of 375 mg / m? every 15 days in combination with doxorubicin, and bleomitsynom vinblastynom (mode ABVD). Dosing and Administration of drugs: The recommended dose is 5 mg / kg body weight (300 - 450 mg) 1 g / day for three weeks, then 300 mg 2 times a folding-camera as maintenance therapy, through the action mistsevopodraznyuvalnu put in / on slowly through fine-needle; Mr estramutsynu be mixed with 250 ml 5% glucose Mr and enter by slow i / v infusion (not earlier than 3 hours); vial contents. Method of production of drugs: lyophilized powder for preparation of district for injection 100 mg, 200 mg, folding-camera mg, 1000 mg in vial. Farmakoterapevychna group. Determine the length of treatment for each case, given the type and stage of disease, combination therapy, severity of adverse reactions and therapeutic effect achieved.