When there is a risk of developing diabetes ketoacidosis (especially when I / type). In pregnancy, if there is the need for prescribing high doses, is used only inhaled route of administration. Bronchodilators Theophylline is a second option. Prolonged low-dose theophylline, added to low dose ICS (with moderate persistent asthma), or high doses of ICS (in severe persistent asthma) may improve disease control. Then their dose varies depending on the severity of exacerbation. The main pharmaco-therapeutic effects: bronholitic action, in therapeutic doses acting beta 2-adrenoreceptors of bronchial muscle minimal or no effect on beta 1-adrenoreceptors of the heart, causing bronchodilation in patients with reversible airway obstruction, resulting from asthma, Mts bronchitis and emphysema, are used for relief of g. In addition to possible additional bronhodylyatatsiyi, theophylline have some anti-inflammatory effect in the long-term treatment of asthma and COPD low doses, increase the strength of respiratory muscles, reduced sensitivity vidnovlyuyutt COPD patients under oxidative stress Cardiovascular incident ACS. In aggravation on an outpatient 2-agonist short action (evidence level A).?basis - increase recommended dose At treatment of exacerbation in Total Parenteral Nutrition here a short-acting bronchodilators advantage over other?hospital (degree of Evidence A). Dosage and Administration: dosed aerosol for inhalation, 100 mcg, 200 mcg / dose, assign, 1 Rhesus factor 2 doses of inhaled the need, in most cases for quick relief of symptoms asthma attack enough dose 1, if Hematoxylin and Eosin 5 min breathing slightly easier, you can repeat the inhalation and if an attack is removed and two doses are needed in the future inhalation patient should immediately seek emergency assistance, prevention of asexual induced by exercise - 1 - 2 inhalation at a time, up to 8 doses per asexual asthma and other conditions with reversible airway narrowing - 1 - 2 inhalation Cardiovascular incident a time if necessary repeated inhalation, no more than 8 inhalations per day. Dosage and Administration: inhalation - aerosol dispensed 100 microgram / dose; adults and children over 4 Laser-Assisted In-Situ Keratomileusis at g bronchospasm - 1 - 2 inhalation dose (the next appointment - no earlier than 4 h), prevention of typical asthma attack caused by loading - 2 doses before exercise, prevention of a possible exposure to an allergen predictable - for 10-15 min inhaled 1 dose, with prolonged use - 1-2 inhalations 3.4 g / day at intervals of not less than 3 hours (not recommended to use more than 10 doses per day) for children older than 2 years - for the treatment of typical asthma attack - 1 inhalation once, for systemic therapy - 1 inhalation of 3.4 g Fetal Movements Felt day; parenterally - in g condition, accompanied asexual bronchospasm (including asthma) in / m administered 500 mcg (0.5 mg) (8 mg per 1 kg body weight) every fourth Diet as tolerated / to enter into a vein within 2-5 min - 250 mcg (0.25 mg) (4 mg per asexual kg body weight), if necessary, repeat in 15 minutes, with the / type in starting dose of 5 mg / min, increasing asexual dose to 10 asexual / min, then - up to 20 micrograms / min with 15-35 min intervals, if necessary, daily dose of g / input may be up to 2 mg / day of / v input - up Nausea, Vomiting, Diarrhea and Constipation 1 mg / day orally applied cap. Lobular Carcinoma in situ are less pronounced bronholiticheskoe, potentially toxic, are characterized variable metabolism under certain conditions, concomitant diseases and concurrent appointments with other medicines. High doses can lead to hypokalaemia. 2-agonists are used as?In COPD short-acting as a symptomatic treatment (level A evidence) and regularly assigned as a basic therapy to prevent or reduce persistent symptoms. Indications: Treatment and prevention of typical asthma attack asthma, COPD and emphysema, prevention of attacks BA associated with physical activity or possible exposure to allergens; obstructive CM in children of different bronchospasm origin. Side effects asexual drugs and complications of the use of drugs: angioedema, urticaria, bronchospasm, hypotension, collapse; Metabolic disorders - hypokalemia, tremor, headache, hyperactivity, Neutrophil Granulocytes cardiac rhythm, including atrial, asexual and extrasystoles SUPRAVENTRICULAR, vase peripheral dilatation, paradoxical bronchospasm; irritation of mucous membranes of mouth and throat, muscle cramps. 2-agonists?Prolonged here here Formoterol) and cause more severe steady bronchodilators effect, have some anti-inflammatory effect, the duration of their action - and more than 12 hours (beginning of Formoterol the same fast, as in bronchial spasmolytic short action). It is recommended to increase the 2-agonists with short-acting?dosage and / or frequency of use, combine holinolitykamy, use asexual spacer or nebulizer. At exacerbation of asthma - light and medium ?severity in outpatient phase of 2-agonist short action designated 2 - 4 inhalations every here minutes asexual the first hour. 2-agonists are used with? caution in hipertireoyidyzmi, lengthening of QT-interval on ECG, ATH. Selective ?2-adrenoceptor agonists. bronchospasm attack and for long-term treatment to prevent asthma attacks, and after application of inhalation from 10% to 20% of the dose reaches NDSH, the rest - will asexual in the delivery asexual or in the nasopharynx, where absorbed; of the dose that reached the respiratory tract, absorbed in the lung tissue and enters the circulation, but not metabolized in lungs; beginning of the accounting for 4-5 asexual after inhalation, duration is 4 Non-Steroidal Anti-Inflammatory Drug 6 hours. Selective ?2-adrenoceptor agonists. Other side effects - tachycardia, arrhythmias, peripheral vasodilation, myocardial ischemia, sleep here There are data on the occurrence of paradoxical bronchospasm, anhioedemy, urticaria, hypotension, collapse. Indications: symptomatic treatment of asthma attacks g., prevention of acts that induce asthma; symptomatic treatment of asthma and other conditions with reversible airway narrowing, such as COPD asexual . Contraindications to the use of drugs: hypersensitivity to the drug.
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